Antibodies to hepatitis C virus in patients with mixed cryoglobulinemia

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Cryoglobulinemia in patients with hepatitis C

Introduction: Cryoglobulinemia is a kind of immunoglobuline that form in various conditions. These imunoglobulines, precipitate in cold environment and restore to soluble state upon rewarming. Nowadays, strong association between cryoglobulines and hepatitis C has been proposed. Methods: This is a descriptive-analytic study in which we included all documented cases of hepatitis C infection wh...

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Hepatitis C Virus Infection and Mixed Cryoglobulinemia

Hepatitis C virus (HCV) chronic infection is recognized as the major cause of mixed cryoglobulinemia (MC). Its persistence represents a continuous stimulus for host immune system with production of circulating immune complexes (ICs), one-third of them with cryoprecipitate property. Several factors contribute to the biological activities of ICs, many of which are not completely known. Among them...

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[Anti-GOR antibodies in type II mixed cryoglobulinemia associated with hepatitis C virus infection].

The frequent association of chronic hepatitic C virus (HCV) infection and type II mixed cryoglobulinemia is considered to be one of the possible signs of interaction between the virus and the immune system. This could also be the case for the appearance of anti-GOR antibodies in serum, as they react with both viral and host antigens. We studied a group of patients with chronic hepatitis C infec...

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Prevalence of hepatitis C virus antibodies and cryoglobulinemia in patients with leukocytoclastic vasculitis.

BACKGROUND Several dermatologic manifestations of hepatitis C virus (HCV) infection have been described. The association of HCV infection, essential mixed cryoglobulinemia and leukocytoclastic vasculitis (LV) have been published mainly in case reports. OBJECTIVE The aim of the present study was to determine the prevalence of HCV infection and cryoglobulinemia in patients with LV. METHODS Tw...

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Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia

Thyroid involvement is a common condition that can be recorded during the natural course of different systemic rheumatic diseases, including the mixed cryoglobulinemia (MC) syndrome or cryoglobulinemic vasculitis. MC is triggered by hepatitis C virus (HCV) chronic infection in the majority of cases; it represents the prototype of autoimmune-lymphoproliferative disorders complicating a significa...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 2010

ISSN: 0004-3591

DOI: 10.1002/art.1780341221